Our focus is on genome analysis, molecular evolution, and protein structural bioinformatics. A long-term goal is to combine these above areas in computational methods to predict and design biological function.
We collaborate closely with a number of labs from Waterloo and beyond.
There are opportunities for graduate students and potential BIOL 499 students.
For prospective students, either bioinformatics/programming or molecular wet-lab experience is strongly recommended. Biology/biochemistry, engineering and computer science students are welcome!
- Doxey AC, Kurtz DA, Lynch MDJ, Sauder LA, Neufeld JD. (2015) Aquatic metagenomes implicate Thaumarchaeota in global cobalamin production. ISME J, 9:461-71.
- Doxey AC, McConkey BJ. (2013) Prediction of molecular mimicry candidates in human pathogenic bacteria. Virulence, 4:1-14
- Broom A*, Doxey AC*, Lobsanov Y, Howell PL, Rose DR, McConkey BJ, Meiering EM. (2012) Modular evolution and the origins of symmetry: design of a threefold symmetric globular protein. Structure, 20:161-71.